Fenofibrate-Nicotinamide Cocrystals: Molecular Docking Studies and Evaluation in Tablet Dosage Form

A Novel Compression-Coated Tablet Dosage Form

www.pharmtech.com new chemical entity often is first formulated as a free-flowing granulation for encapsulation within hard gelatin capsules. During the course of clinical development, the drugcontaining granulation usually is modified for compaction into a tablet product. The tablet product subsequently may be film coated for taste masking, identification, or other purposes. Tablets are the mo...

Development and Validation of Reversed-Phase HPLC Method for Simultaneous Estimation of Rosuvastatin and Fenofibrate in Tablet Dosage Form

A simple, precise and accurate reversed-phase liquid chromatographic method has been developed for the simultaneous estimation of Rosuvastatin and Fenofibrate in tablet formulations. The chromatographic separation was achieved on (Inertsil ODS, 250 x 4.6mm, 5μ column) analytical column. And mobile phase as mixture of Water (pH adjusted to 2.5 with ortho phosphoric acid) and acetonitrile in rati...

acetaminophen, diclofenac, chlorpheniramine and magnesium trisilicate in one dosage form; oral tablet formulation and physicochemical evaluation

Spectrophotometric determination of lacidipine in bulk and tablet dosage form

New, simple, accurate, sensitive, economical, and reproducible UV-spectrophotometric method was developed and validated for the estimation of Lacidipine in bulk and tablet dosage form. Lacidipine shows maximum absorbance at 615.7 nm and linearity (Beer’s Lamberts law) was found to be in the range of 10-70 μg/ml. The apparent molar absorptivity and Sandell’s sensitivity coefficient were found to...

Industrial Process Validation of Tablet Dosage Form: a Review

The present article gives an introduction and general overview on process validation of pharmaceutical manufacturing process especially tablet manufacturing process. The principal objective of dosage form design is to achieve a predictable therapeutic response to a drug included in a formulation which is capable of large scale manufacture with reproducible product quality. Solid dosage forms in...